AI‑Based Clinical Decision Support in Primary Care

A real‑world study across 39,849 patient visits in Nairobi

Discover how Penda Health and OpenAI cut diagnostic and treatment errors—while preserving clinician autonomy—in one of the world’s largest live evaluations of an LLM co‑pilot.

WHY THIS STUDY MATTERS

Evidence, not hype

Large language models can ace exam‑style vignettes, but do they help real patients? Our cluster‑assigned quality‑improvement study measured the effect of AI Consult during everyday care in 15 busy Kenyan clinics.

Front‑line‑first design

AI Consult surfaces only when needed, uses a simple “traffic‑light” UI, and lets clinicians override or accept advice with a single click—ensuring workflow fit and clinician trust.

Scalable blueprint

We openly share the implementation playbook—data pipelines, change‑management tactics and regulatory safeguards—so other systems can replicate (or improve upon) our results.

KEY FINDINGS AT A GLANCE

32%

Reduction

History-taking errors

10%

Reduction

Investigation errors

16%

Reduction

Diagnostic errors

13%

Reduction

Treatment errors

75%

Clinicians reporting "quality substantially improved"

“AI provides an extra layer of comfort and confidence. It’s like having a fellow consultant in the room as i attend to my patients”

Adah - Clinician Penda Health

INSIDE THE PAPER

A full methods section, statistical code snippets and survey instrument are included in the appendix for teams who want to run similar evaluations.

109 clinicians, 39,849 patient visits, 15 clinics

Scale & setting

Cluster‑assigned intervention with independent physician raters and supplemental LLM raters to test concordance.

Design

AI Consult only interrupts when probability of harm is high, minimizing alert fatigue.

Safety net, not autopilot

Active coaching and feedback loops made the effect size grow over time as clinicians learned from the tool.

Uptake strategies

START YOUR HIGH‑VALUE AI JOURNEY

Ready to translate evidence into action?

Download the study, watch the overview, and contact our team to explore pilots, joint research or knowledge‑sharing sessions.